Answer:
A. More than 300 rivers drain into Siberia's Lake Baikal, which holds 20% of the world's fresh water, more than all the North American Great Lakes combined.
Step-by-step explanation:
The option B is incorrect because it has the preposition "With" which mess the whole statement
The option C is incorrect because the pronoun "It" before "holds" is not necessary
Option D is incorrect because the word "while" makes the sentence incoherent.
Option E is incorrect because it appears like the statement is making a comparison between baikal with more than all the North American great lakes.
Hence, the correct answer is option A.