Answer: No, lactose metabolism will stop.
Step-by-step explanation:
If the binding site of ribosome with mRNA gets mutated then the ribosome will not be able to translate the mRNA. As a result of this no functional enzymes will be produced or synthesized in this process like permease and beta-galactosidase.
In the absence of these enzyme proteins the lactose will not be metabolized by the cells of the body.