Answer:
The Ninety-five Theses led to the Reformation, a break with the Roman Catholic Church that previously claimed hegemony in Western Europe. Humanism and the Renaissance therefore played a direct role in sparking the Reformation, as well as in many other contemporaneous religious debates and conflicts.
During the Renaissance, people increasingly began to see the world from a human-centered perspective. This had a powerful impact upon religion. Increasingly, people were paying more attention to this life rather than the afterlife. Eventually, humanism brought about a spirit of skepticism.
Renaissance art, painting, sculpture, architecture, music, and literature produced during the 14th, 15th, and 16th centuries in Europe under the combined influences of an increased awareness of nature, a revival of classical learning, and a more individualistic view of man.
-Astolfo