Answer:
![=\frac{e-\sqrt[16]{e}}{4}](https://img.qammunity.org/2021/formulas/mathematics/college/j1jhu71yf8smwqzigxug0lfdsonns4zy4j.png)
Explanation:
So we have the definite integral:

Again, we can use u-substitution. Let u equal 1/x^4. So:

Find the derivative:

Divide by -4. So du is:

Of course, we also need to change our bounds. Substitute 1 and 2 into u:

Therefore, our new bounds are from 1 to 1/16.
So, make the substitutions:

The integral of e^u is just e^u. So:

Evaluate for the bounds:

Simplify:
![=-\frac{\sqrt[16]{e}-e}{4}](https://img.qammunity.org/2021/formulas/mathematics/college/r2p9gylafrkabaa57zpay1imlyvc7pxdm3.png)
Distribute:
![=\frac{e-\sqrt[16]{e}}{4}](https://img.qammunity.org/2021/formulas/mathematics/college/j1jhu71yf8smwqzigxug0lfdsonns4zy4j.png)
And we're done!