A bottle of the medicine contains 0.5 kilograms of the medicine. One dose of the medicine is 20 grams for a child and 45 grams for an adult. The number of grams used can be calculated with the formula 20C + 45A, where A is the number of adult doses and C is the number of child doses. If a medical assistant needs to give a dose of the medicine to 12 adults and 10 children, will there be enough medicine in the bottle? If not, how many more grams will be needed?