Question

Which is an example of an idiosyncratic reaction?

a. Nausea after taking an antibiotic agent
b. Excitement and agitation after taking a sedative
c. Increased clotting time after taking heparin
d. Sedation after taking a sleeping pill

Answer 1

Answer ; A

Idiosyncratic reactions are unpredictable and not explained by the pharmacologic properties of the drug. An example is the individual with infectious mononucleosis who develops a rash when given ampicillin.

Definition. Idiosyncratic drug reactions are adverse drug reactions that do not occur in most patients at any dose and do not involve the known pharmacological properties of the drug.

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