You can use
cos(theta) = u · v / ║u║║v║
that will come out to:
u = 2 x (-4) = -8
v = 3 x (-8) = - 24
u · v = -16
║u║ =
=

║v║ =

cos(theta) = -16/2

and to find (theta), you can now do
theta = (cos^-1) ( -16/2
)
I don't have a calculator, but you can solve that final problem to find theta