Answer: es; están
Sentence: ¡El señor Moreno es tan agradable! Sus amigos están en México.
Translation: Mr. Moreno is so nice! His friends are in Mexico.
Step-by-step explanation:
The subject in the first sentence is "señor Moreno", that is a first-person singular, so the verb must be conjugated in this form: Él es agradable.
The subject in the second sentence is "amigos", that is a first-person in the plural, so the verb must be conjugated in this form: Ellos están en México.
Spymore