Question

(d) Researchers discovered a strain of C. Parvum that expresses a functional variation of the lactate dehydrogenase gene. A DNA sequence comparison showed that the variant differs from the normal sequence in the region that codes for the enzyme's allosteric site. Predict the effect of FX11 treatment on C. Parvum cells that express this variant of lactase dehydrogenase. Provide reasoning to support your prediction. Explain how gossypol and FX11 might be used as drugs to treat C. Parvum infections in humans without negatively affecting human cells.

Answer 1

This mutation will produce an enzyme with modified hydrogenase activity

Step-by-step explanation:

The allosteric site is critical to switch on/off the enzyme activity. The enzymes with allosteric activity are regulated by binding an effector molecule in a different site to the active site of the enzyme.