Answer:
During interphase, replication of the genome DNA occurs during S phase of the cell cycle.
Explanation:
S phase is also called synthesis phase. S phase occurs between G1 and G2 phase of interphase. S phase is the second stage of interphase which occurs before mitosis process of cell division. The cell spends most of the time in interphase where replication of DNA occurs. In this replication, a copy of DNA molecule is produced which is distributed in the daughter cells after mitosis cell division occurs.