Question

The Sox2 protein is an early marker of neural tissue. Imagine a researcher removes a region of cells from an area of a gastrulating embryo he believes to be neural-specified, and places them in neutral culture medium; however, he doesn't observe any Sox2 expression after several days, and the cells do not take on a neuron-like appearance. What could be an explanation for this?

Answer 1

the Sox2 protein is a prime factor of making neutral tissues and has an important role in, initiating neural induction and maintaining neural progenitor stem cell properties throughout neural differentiation.

a researcher removed a group of cells believing that it was the neural specified area and placed them in a neutral culture medium. he did not observe and those cells did not appear as a neuron-like appearance because--

The removed cells needed to be exposed to a variety of "non-neural" proteins to demonstrate neural specification.

it was left unattended and non-neural proteins were also not been provided to that culture.