Final answer:
The two populations compared in the study were women whose mothers took the drug DES during pregnancy and those whose mothers did not. The data in the study were obtained through an observational study. A descriptive statistic can be used to estimate the number of women with tissue abnormalities out of 1000 in the population of women whose mothers took the drug DES during pregnancy.
Step-by-step explanation:
a. The two populations in the study were: 1) women whose mothers took the drug DES during pregnancy and 2) women whose mothers did not take the drug.
b. The data in this study were obtained through an observational study, specifically a cohort study. This means that the researchers observed and compared the outcomes between the two groups of women without directly manipulating any variables.
c. A descriptive statistic that could be used to estimate the number of women out of 1000 in the population of women whose mothers took the drug DES during pregnancy and developed tissue abnormalities is:
Number of women with tissue abnormalities in the sample: 63
Descriptive statistic: (63 / 3980) * 1000 = 15.83
Therefore, an estimate is that 15.83 out of 1000 women in this population have tissue abnormalities that might lead to cancer.
d. Since the study only reported that women whose mothers took the drug DES during pregnancy were twice as likely to develop tissue abnormalities, without providing an exact percentage, it is not possible to estimate the number of women without more specific information.
e. Medical studies often use a relatively large sample size, like 3980, to increase the reliability and representativeness of the findings. A larger sample size helps to reduce the chance of biased or random results and increases the generalizability of the findings to the larger population.