Answer:
It is not possible for the US to stay out of European affairs, but also the affairs of all other countries today.
Step-by-step explanation:
The United States of America is a hegemonic power that has to exhibit influence on its geopolitical spheres of interest if it is to keep the status of hegemonic power, and keep political, social and economic advantages that come with it.
The US along with the European Union has been the flagship in the promotion of Western values and the way of life in the 20th century. The beginning of the 21st century is marked by the rise of Eastern hegemonic powers, like China and Russia. US can not retrieve to complete isolationism if it does not want to experience the extensive interference of such powers into US geopolitical spheres of interest (for example, Ukraine).