Question

Given that both human cells and pathogens synthesize proteins at ribosomal sites, how can antimicrobial agents that target this process be safe to use in humans?

Answer 1

Antimicrobial agents may be defined as the agents that can kill or inhibit the growth of the microorganism. These agents are important and can safe the humans from the pathogens.

The pathogen and human ribosomes is quite different. Human is a eukaryotes and contains the 80'S ribosomes whereas prokaryotes have 70'S ribosomes. In the preparation of the antimicrobial agents, the advantage can be taken as the bacteria or prokaryotes have different ribosome subunit. The drugs that can selectively target the pathogens ribosomes and stops the translation whereas shows no effect on human's translation.