Answer: x+4
This is because the given expression factors to (x+4)(x+4), which condenses to (x+4)^2.
To factor, think of two numbers that A) multiply to 16, and B) add to 8. Those values would be 4 and 4
4+4 = 8
4*4 = 16
So that's how we end up with (x+4)(x+4). You can use the FOIL rule to expand that out and get x^2+8x+16 again to help verify you have the correct factorization.