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Describe in detail, using academic vocabulary, how the medical conditions Asthma and diabetes can prevent the cells from not getting enough moleculesto function. Be specific in your response. Please HELP this is due soon and it's over half my grade!

User Bonhoffer
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Asthma diabetes prevent
User Roger Binns
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Asthma and diabetes can prevent the cells from getting enough molecules to function.

ASTHMA

  • The clinical manifestations of asthma are caused by obstruction of the conducting airways of the lung. . Asthma involves an integrated response in the conducting airways of the lung to known or unknown triggers, it is a multicellular disease, involving abnormal responses of many different cell types in the lung. There are two cell types which are ultimately responsible for the major symptomatic pathology in asthma—epithelial cells that initiate airway inflammation in asthma and are the source of excess airway mucus and smooth muscle cells that contract excessively to cause symptomatic airway narrowing.

  • Asthma puts one's lungs into a weakened state, making them more susceptible to a second or third attack. The muscles in one's lungs tighten during an asthma episode, and the bronchial tubes may become swollen or otherwise irritated. In worst-case scenarios, one may experience what is known as airway remodeling. This only occurs in long-term asthma patients who have not taken care of themselves and their condition. With asthma remodeling, the airways naturally cannot receive as much air. That makes asthma attacks more likely. Worse yet is that airway remodeling is impervious to most treatments, including asthma medications. This is due to scarring on the lungs.

DIABETES

  • When you have type 2 diabetes, your fat, liver, and muscle cells do not respond correctly to insulin. This is called insulin resistance. As a result, blood sugar does not get into these cells to be stored for energy. Diabetes is a complex, heterogeneous condition that has beta cell dysfunction at its core. Many factors (e.g. hyperglycemia/glucotoxicity, lipotoxicity, autoimmunity, inflammation, adipokines, islet amyloid, incretins and insulin resistance) influence the function of pancreatic beta cells.

User Pavel Vorobyov
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