Question

A genome-wide association study involves searching the genomes of many people in order to find genetic variations associated with common diseases such as cancer, asthma, and diabetes. These studies are possible because of computer databases that allow researchers to compare the genomes of people who do not have a particular condition with the genomes of people who have the condition. In order to do this type of testing, researchers need blood samples or cheek swabs from people. Obtaining these samples is necessary because blood and cheek cells contain___________

A. plasma and platelets
B. a complete set of DNA
C. essential proteins and amino acids
D. a large number of neutrophils

Answer 1

Blood samples or cheek swabs are necessary for genome-wide association studies because they contain a complete set of DNA, enabling the comparison of genetic variants associated with diseases.

Step-by-step explanation:

In genome-wide association studies (GWAS), researchers obtain blood samples or cheek swabs because these cells contain a complete set of DNA. This complete set of DNA is crucial for comparing genetic variants like single nucleotide polymorphisms (SNPs) between people with a certain condition and those without it. Blood and cheek cells provide the necessary genetic material for identifying genetic differences that may contribute to common diseases such as cancer, asthma, and diabetes.

GWAS leverage databases, like the International HapMap Project, to analyze the genomes from hundreds of individuals, identifying groups of SNPs and their links to diseases. By comparing large groups of people, researchers can find even subtle genetic variants that influence disease risk. This approach has opened doors to personal genomics, and potential insights into disease mechanisms and therapies.

Answer 2

Answer: B. a complete set of DNA

Step-by-step explanation: