Answer:
The correct answer is d. rely on end-users to develop it themselves.
All of the other options (a. develop a custom application in-house, b. rely on an external vendor to build the system, and c. purchase a software package and customize it) are common ways to approach the creation of a new information system. These approaches involve hiring professionals or purchasing software packages to design, build, and implement the system.
Option d, relying on end-users to develop the system themselves, is not a fundamental way to approach the creation of a new information system. End-users are typically not trained in the technical skills needed to design and build an information system, and they may not have the necessary expertise or resources to do so. It is generally more effective to rely on professionals or pre-existing software packages to create a new information system.