Question

An injection contains 5 million international units (MIU) of interferon alpha-n3 (ALFERON N) proteins per milliliter. The recommended dose is 0.05 mL. The literature states that the activity of interferon alpha-n3 is approximately equal to 2.6 × 108 international units/mg of protein.

Calculate (a) the number of international units and
(b) the micrograms of interferon alfa-n3 proteins administered per dose.

Answer 1

A patient with a body surface area (BSA) of 0.82 m² should be given 1.64 million of units of Interferon alpha 2b, according to the recommended dose.

Step-by-step explanation:

Interferon alpha 2b (IFN α-2b) is a biological product used to stimulate the immune system and fight diseases such as hepatitis B and C, leukemia and other types of cancer.

The usual dose of IFN α-2b is 2 to 3 million units per dose, although some circumstances may require a higher dose.

If a patient has an estimated AFB of 0.82 m² and the recommended dose is 2,000,000 units/m²:

IFN a-2b dose = 2,000,000 units/m2 X 0.82 m2

IFN a-2b dose = 1.640.000 UI

The patient, according to the dose and his BSA should receive 1.64 million units of IFN α-2b.

Step-by-step explanation: