Question

1. The graph below shows rate of reaction data for 2 different enzymes. One of these enzymes is found in the stomach, the other is found in the mouth.a) Both these enzymes have the same optimum pH, TRUE or FALSE?2. Explain, in terms of bonding, why the rate of reaction gradually falls once the pH increases above the optimum rather than denaturing straight away.

Answer 1

According to the graph, the enzymes have different optimum pH as the curves do not overlap.

The answer of question a is: False

In terms of bonding, the rate of the reaction falls gradually once the pH increases above the optimum rather than denaturing, because the enzyme might suffer certain modifications that may decrease its affinity towards the sustrate, or alter its active site, but not necessary degrade, or denature the whole molecule. This proccess doesn't occur at a minimal pH change.