Question

During transcription, RNA polymerase synthesizes RNA from a DNA template with the help of accessory proteins.

a. True
b. False

Answer 1

The statement is true; RNA polymerase synthesizes RNA from a DNA template with the help of accessory proteins during transcription, binding to a promoter, and using rNTPs including uracil.

Step-by-step explanation:

The statement about transcription is true. During this process, RNA polymerase synthesizes RNA using a DNA template. The enzymatic activity involves a complex interplay of different components: RNA polymerase itself, accessory proteins known as transcription factors, a DNA template, ribonucleotide triphosphates (rNTPs) like ATP, UTP, CTP, and GTP, and divalent metal ions such as Mg2+. RNA polymerase starts the synthesis of RNA at the 3' end of the growing RNA strand and continues to elongate it by adding nucleotides complementary to the antisense strand of the DNA in a 5' to 3' direction. Uracil (U) is used in place of thymine (T) when paired with adenine (A). Eukaryotic transcription also requires the RNA polymerase to bind to a sequence called a promoter, whereby the DNA unwinds to form an open complex that enables RNA polymerase to begin nucleotide addition. Transcription proceeds until it reaches a stop or terminator sequence.

Answer 2

The correct answer is a. True

Step-by-step explanation:

The information to produce a protein is coded in the cells in deoxyribonucleic acid (DNA). Transcription is the process in which a DNA sequence is copied into a ribonucleic acid (RNA) sequence. This RNA sequence is a messenger RNA (mRNA) because it will be then translated into a functional protein. For this, the DNA sequence is read and an RNA strand is synthesized by an RNA polymerase (an enzyme that synthesizes RNA molecules from a DNA template). During the process participate other proteins, such as DNA binding proteins, activators, coactivators, etc. (accessory proteins).