Hello. You have not informed us the text to which this question refers, which makes it impossible for this question to be answered accurately.
However, to make inferences in a text, it is necessary that the reader uses clues and information covered in the text itself so that the reader can discover the purposes and meanings that the author is trying to convey. Accordingly, we could consider the option "How does the last line of the third paragraph frame the author's argument throughout?" as the correct answer, since this option uses an element of the text itself to unravel the author's intentions.