Answer:
The correct answer is - option D. nonsense and frameshift.
Step-by-step explanation:
If there is a change in the sequence of DNA resulting in premature stop codon mRNA during transcription is known as a nonsense mutation and result in a non-functional protein.
a frame-shift mutation takes place when at least two nucleotides are altered and there are less chances to be changed by two others coding for the same nucleotide. It leads to a non-functional protein.