Final answer:
The Treaty of Ghent ended the War of 1812.
Step-by-step explanation:
The significance of the Treaty of Ghent is that it ended the War of 1812. The treaty was negotiated between British and U.S. diplomats in Belgium in 1814 and was signed in December of that year. While the British had initially sought to resolve conflicts in the Americas and the war was still ongoing, the treaty's ratification by the American government in February 1815 officially brought an end to the war.