Final answer:
DNA-histone complexes inhibit transcription in eukaryotic cells.
Step-by-step explanation:
The DNA-histone complexes that are formed in eukaryotic cells directly inhibit transcription. Histones are proteins that help organize and compact DNA into a structure called chromatin. When DNA is tightly wound around histones, it becomes less accessible for the transcription machinery to access and transcribe the genes. Therefore, the formation of DNA-histone complexes inhibits the process of transcription.