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Rimonabant is a CB1 receptor antagonist that was used as an anti-obesity agent. Why was the drug removed from the global market in 2009?

A. it was ineffective as an anti-obesity agent
B. concern about dangerous psychological side effects
C. marijuana became legal in 20 U.S. states
D. dronabinol was found to be more effective for obesity

1 Answer

6 votes

Final Answer:

Genetic testing for the HFE gene mutations (C282Y and H63D) is crucial to confirm the diagnosis of hemochromatosis in this patient.

Step-by-step explanation:

Considering the patient's elevated iron studies and the suspicion of hemochromatosis, genetic testing for HFE gene mutations is a non-invasive and reliable method for confirmation. In hereditary hemochromatosis, the most common form of iron overload, mutations in the HFE gene are often present. While liver biopsy is a gold standard for assessing iron levels, it carries risks and may not be necessary if genetic testing confirms the diagnosis. Positive results for C282Y or H63D mutations support the diagnosis, allowing for appropriate management, such as therapeutic phlebotomy.

User Andrii Rusanov
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