Final answer:
Drivers must exercise caution and drive on the right-hand side when on a road without a centerline to avoid head-on collisions with oncoming traffic.
Step-by-step explanation:
When driving on a road with no centerline where vehicles come from each direction, drivers must exercise additional caution and drive on the right-hand side of the road or as far right as possible. This provides a buffer to avoid head-on collisions with oncoming traffic. It also is important to be mindful of speed limits and surroundings, as a lack of a centerline can sometimes indicate less formal road conditions or narrower lanes.