Final answer:
The diagnosis indicated by the absence of oral lesions, presence of pruritis, and a negative Nikolsky sign is Bullous pemphigoid, which is treated with systemic corticosteroids and immunosuppressive agents.
Step-by-step explanation:
The question 'no oral mucosal lesions + pruritis + negative nikolsky sign. Dx? Bullous pemphigoid Tx?' pertains to the diagnosis of a skin condition with specific clinical features and its treatment. The lack of oral mucosal lesions, presence of pruritis (itching), and a negative Nikolsky sign (a diagnostic sign where the skin does not easily separate when rubbed) suggests the diagnosis of Bullous pemphigoid. This condition is characterized by large, fluid-filled blisters that don't usually affect the mucous membranes and is often not as painful as similar blistering conditions. Treatment for Bullous pemphigoid typically involves systemic corticosteroids to reduce inflammation, along with other immunosuppressive agents such as azathioprine or methotrexate, depending on severity.