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Histidine becomes.. (what's the cofactor?)

a. NAD+
b. FAD
c. Pyridoxal phosphate
d. Heme

1 Answer

6 votes

Final answer:

Histidine is associated with the cofactor Flavin adenine dinucleotide (FAD), which is used as a versatile coenzyme in various oxidation reactions in flavoproteins.

Step-by-step explanation:

The question is asking which cofactor histidine becomes associated with. Based on the provided information, histidine is linked through the flavin ring C=0 to one protein histidine residue in the context of a flavoprotein, specifically referencing Flavin adenine dinucleotide (FAD).

In biochemical reactions, FAD acts as a versatile coenzyme involved in various oxidation reactions, unlike its counterpart NAD+, which is predominantly known for its role in oxidation-reduction reactions to form NADH.

Additionally, the heme cofactor is associated with cytochromes and not directly with histidine as a transformed cofactor, whereas pyridoxal phosphate is commonly linked with amino acid metabolism.

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