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Acetaminophen is first combined with the sodium hydroxide/ethanol solution, followed by the addition of 1-iodobutane. Explain briefly the purpose of this step.

User Ohmantics
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Final answer:

The purpose of combining acetaminophen with the sodium hydroxide/ethanol solution followed by the addition of 1-iodobutane is to facilitate the esterification process.

Step-by-step explanation:

The purpose of combining acetaminophen with the sodium hydroxide/ethanol solution followed by the addition of 1-iodobutane is to facilitate the conversion of acetaminophen into an ester. This step is known as esterification and is an important process in organic chemistry.

Esterification involves the reaction between a carboxylic acid and an alcohol in the presence of an acid catalyst. In this case, acetaminophen, which contains a carboxylic acid group (–COOH), reacts with the sodium hydroxide/ethanol solution to form the sodium salt of acetaminophen, which is an intermediate compound.


This intermediate compound then reacts with 1-iodobutane, an alkyl halide, to form the ester. This esterification step is important because it allows the synthesis of a new compound with different properties and functionality.

User Holgero
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