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Pathology of Frontotemporal Dementia/Pick's Disease?

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Final answer:

Frontotemporal Dementia involves degeneration of the frontal and temporal lobes and is characterized by Pick bodies and changes in behavior and language. It is similar to Parkinson's disease in regard to the presence of abnormal protein aggregates and the potential influence of genetic and environmental factors.

Step-by-step explanation:

The pathology of Frontotemporal Dementia, also known as Pick's Disease, involves the progressive degeneration of the frontal and temporal lobes of the brain. It is marked by the presence of Pick bodies, which are abnormal protein aggregates, similar to the Lewy bodies found in Parkinson's disease.

Symptomatic of the disease are changes in behavior, personality, and language due to the affected brain regions. Unlike Parkinson's, which affects the substantia nigra and leads to motor symptoms, Frontotemporal Dementia presents primarily with cognitive and social deficits. In both diseases, genetic and environmental factors may play a role, though a large number of cases have unknown etiologies.

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