Final answer:
You are not required to inspect cargo and securing devices if the load is sealed and you're instructed not to open it, to comply with security or customs.
Step-by-step explanation:
The only circumstance in which you are not required to inspect your cargo and load securing devices is if your load is sealed and you have been ordered not to open it. The relevant regulations acknowledge that the driver may not always have the ability to inspect the cargo, particularly in the case where the load is sealed for security or customs reasons. It is important to follow these instructions closely to ensure compliance with transportation laws and regulations.