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What disease is associated with this spinal cord lesion?

1) Tabes dorsalis (tertiary syphilis)
2) Other

User Gene Bo
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1 Answer

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Final answer:

A spinal cord lesion associated with syphilis is indicative of tertiary syphilis, particularly tabes dorsalis. This stage of syphilis infection can cause severe damage to internal organs and the nervous system, including granulomatous lesions known as gummas and neurosyphilis, leading to a range of neurological symptoms.

Step-by-step explanation:

Tabes Dorsalis and Spinal Cord Lesions

Tabes dorsalis is a form of neurosyphilis, which represents the tertiary stage of syphilis infection. This stage may occur 10 to 20 years after the initial syphilis infection. In tertiary syphilis, the disease may cause severe and potentially fatal damage to internal organs, including the brain, heart, liver, or bones. The spinal cord can also be affected, resulting in various neurological symptoms such as paralysis, blindness, seizures, and dementia. Specifically, tabes dorsalis is associated with degeneration of the dorsal columns of the spinal cord and dorsal roots of the spinal nerves, leading to poor coordination and sensory deficits.

Gummas, which are granulomatous lesions, can develop in a variety of locations, including the bones and internal organs, and are indicative of tertiary syphilis. These lesions can cause massive tissue damage. Moreover, cardiovascular syphilis can lead to life-threatening conditions such as aortic aneurysm or coronary stenosis. In the context of the spinal cord, lesions associated with tertiary syphilis would not typically result from traumatic events like a motorcycle accident, which could cause paraplegia or hemiplegia due to hemisection of the spinal cord. Instead, the damage in syphilis is usually more gradual and insidious due to the syphilitic infection.

Given these considerations, a lesion in the spinal cord in the context of syphilis is most likely associated with tertiary syphilis, specifically tabes dorsalis, rather than other causes such as traumatic injury or birth defects like spina bifida, which have different etiologies and manifestations.

User Florent Cardot
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