Final answer:
The first step in the Evidence-Based Practice process involves the nurse manager asking a clear and structured clinical question following the PICO format to identify the issue at hand.
Step-by-step explanation:
The question posed by the nurse manager that reflects the first step of the Evidence-Based Practice (EBP) process is likely to be related to identifying and clearly articulating the clinical question or problem. In evidence-based practice, the initial step involves asking a concise and answerable question that usually follows the PICO format (Patient, Intervention, Comparison, and Outcome). This structured approach assists in searching for relevant evidence and research studies that address the identified issue.