Question

Which of the following cell types can process peptide fragments and load them onto major histocompatibility complex class II (MHC II) molecules for presentation to CD4+ T cells?

a) CD8+ T cells.
b) Neutrophils.
c) Dendritic cells.
d) CD3+ T cells.
e) CD56+ natural killer (NK) cells.

Answer 1

Dendritic cells are professional antigen-presenting cells that can process peptide fragments and present them with MHC II molecules to CD4+ T cells; therefore, the correct answer is c) Dendritic cells.

Step-by-step explanation:

The cell types that can process peptide fragments and load them onto major histocompatibility complex class II (MHC II) molecules for presentation to CD4+ T cells are professional antigen-presenting cells (APCs). These cells include macrophages, dendritic cells, and B cells. Therefore, the correct answer to the question is c) Dendritic cells.

Dendritic cells phagocytose pathogens and present processed antigen fragments in conjunction with MHC II molecules, activating T cells. This is part of the adaptive immune response. Macrophages and B cells also have this capacity, but they are not listed as options in the question. Other cells like neutrophils, CD8+ T cells, CD3+ T cells, and CD56+ NK cells do not present antigens in this manner.