Final answer:
Transfusing Rh-negative RBCs to an Rh-positive patient can lead to hemolytic reactions due to the production of antibodies against the Rh antigen.
Step-by-step explanation:
The danger of transfusing donor Rh-negative red blood cells (RBCs) to an Rh-positive patient is the potential for hemolytic reactions. When Rh-positive RBCs are transfused into an Rh-negative individual, the recipient's immune system may produce antibodies against the Rh antigen, leading to the destruction of the transfused RBCs. This can cause symptoms such as fever, chills, itching, hives, shortness of breath, and low blood pressure.