Question

If a type-A person contains anti-M in their serum, What might their reverse grouping type as?

1) A
2) AB
3) B
4) O

Answer 1

A type-A person with anti-M in their serum would have a reverse grouping as type A because reverse grouping looks for anti-A and anti-B antibodies, not other antibodies like anti-M.

Step-by-step explanation:

If a type-A person contains anti-M in their serum, their reverse blood grouping would be type-A. In blood typing and transfusion medicine, reverse grouping involves testing the serum of the individual against known A and B blood cells. Since the individual has type-A blood, they have the A antigen present on their red blood cells and, based on standard ABO blood group reactions, would not normally have anti-A antibodies in their plasma. The presence of anti-M suggests an additional blood group system beyond the basic ABO and Rh systems. However, this factor is not considered in the reverse typing for ABO grouping because reverse typing looks for the presence of anti-A and anti-B antibodies, not other antibodies like anti-M. Therefore, with type A having the A antigen and assuming no anti-A nor anti-B antibodies are present (which would be consistent with type A), the reverse grouping would still be type A.