Final answer:
AB titers specific to antigens from the ABO system are typically highest when the patient is a newborn.
Step-by-step explanation:
The titers specific to antigens from the ABO system are typically highest when the patient is a newborn. ABO antibodies are produced in the first years of life through sensitization to similar antigens commonly found in the environment. For example, anti-A antibodies are thought to originate from an immune response to an antigen on the influenza virus, and anti-B antibodies are likely formed in response to other similar antigens.