Final answer:
The proper sequence of wound healing by first intention is 1)Inflammatory, 2)Proliferation, and 3)Remodeling. These stages include initial inflammation, tissue regeneration with new cells and collagen, and final tissue maturation and scar formation.
Step-by-step explanation:
The correct order of the phases of wound healing by first intention are: Inflammatory, Proliferation, and Remodeling. Wound healing is a complex process involving a series of orchestrated events. Initially, the Inflammatory phase occurs as the body responds to injury with vasodilation and fluid leakage, leading to redness, warmth, swelling, and pain. This phase also involves the removal of toxins and waste products and sets the stage for the healing process.
Following the Inflammatory phase is the Proliferation phase, where fibroblasts deposit collagen and other cells work to replace the lost tissue. New blood vessels form during angiogenesis, and this vascularization establishes granulation tissue. The final stage is the Remodeling phase, where the wound matures and gains tensile strength over time. Collagen fibers realign, the wound contracts, and eventually, a scar may form, indicating the completion of the healing process. The answer is option 1, 2, and 3.