Complementary base pairing
Step-by-step explanation:
DNA probes are the single stranded stretches of nucleotides that are complementary to the original strand. DNA probes are used in various molecular technologies like polymerase chain reaction and DNA finger printing.
DNA probes can only hybridize with the specific complementary base pairs. Hence, complementary base pairing determines the specificity of DNA probe.
Thus, the correct answer is option (D).