Question

A 34-year-old female is undergoing tumescent liposuction of the abdomen and flanks. Peak serum levels of local anesthetic from the tumescent solution are most commonly seen in what time frame?

Answer 1

Peak serum levels of local anesthetic from the tumescent solution during liposuction are most commonly seen within 12 hours after the procedure.

Step-by-step explanation:

Tumescent liposuction involves the infusion of a large volume of tumescent solution into the subcutaneous fat layer before the fat removal process. This solution typically contains local anesthetics such as lidocaine. The peak serum levels of local anesthetic occur as a result of absorption from the tumescent solution, and they are commonly observed within the first 12 hours after the liposuction procedure. This timeframe represents the period when the concentration of the local anesthetic in the bloodstream is at its highest.

Monitoring and understanding the pharmacokinetics of the local anesthetic used in tumescent liposuction are crucial for ensuring patient safety and managing potential side effects associated with systemic absorption.