Final answer:
High-risk HPV can neutralize p53, The best studied of these proteins is p53. In a normal cell, p53 detects DNA damage in the cell's genome and either halts the progression keeping the cell in a state in which fast growth is possible and impairing apoptosis, allowing mutations to accumulate in the cellular DNA.
Step-by-step explanation:
When the high-risk types of HPV enter a cell, two viral proteins are used to neutralize proteins that the host cells use as checkpoints in the cell cycle. The best studied of these proteins is p53. In a normal cell, p53 detects DNA damage in the cell's genome and either halts the progression of the cell cycle—allowing time for DNA repair to occur-or initiates apoptosis.
Both of these processes prevent the accumulation of mutations in a cell's genome. High-risk HPV can neutralize p53, keeping the cell in a state in which fast growth is possible and impairing apoptosis, allowing mutations to accumulate in the cellular DNA.