Final answer:
The induced-fit model explains how enzymes and substrates undergo dynamic conformational changes upon binding, enabling a better fit and increasing the rate of the reaction.
Step-by-step explanation:
The conformational changes of the active site that allow for a better fit between the enzyme and its substrates are a result of the induced-fit model.
According to this model, both the enzyme and substrate undergo dynamic conformational changes upon binding. The enzyme contorts the substrate into its transition state, thereby increasing the rate of the reaction. In the induced-fit model, the substrate brings about a conformational change in the enzyme by binding to it.