Question

What is DNA scrunching?

A. Occurs during transcription when sigma 1.1 mimics DNA in the DNA channel, and the actual DNA molecule tries to enter the channel

B. Occurs during transcription when the length of the nascent transcript is limited by RNAP rudder to 6-9 nts

C. Occurs during transcription when double-stranded DNA sinks into the channel and hits the RNAP active site wall

D. Occurs during transcription and abortive cycling; 6-9 nts of DNA template are pulled into the RNAP active site where the template is bunched up

Answer 1

DNA scrunching is a process that occurs during transcription where the DNA sinks into the RNAP channel and hits the active site wall, causing it to bunch up. This facilitates the separation of DNA strands and the synthesis of RNA.

Step-by-step explanation:

DNA scrunching refers to the process that occurs during transcription where the double-stranded DNA sinks into the RNA polymerase (RNAP) channel and hits the RNAP active site wall, causing the DNA molecule to bunch up.

This process is a result of the movement of the RNAP along the template DNA, creating tension in the DNA molecule. The scrunching facilitates the separation of the DNA strands and allows for the synthesis of RNA.