Question

Which cytokine helps regulate the hematopoiesis of cells of the immune system?

A. G-CSF
B. TNF-α
C. IFN-γ
D. IL-5

Answer 1

The cytokine that regulates the hematopoiesis of immune system cells is A. G-CSF (Granulocyte Colony-Stimulating Factor), which is a key factor in the production and maturation of granulocytes from hematopoietic stem cells.

Step-by-step explanation:

The cytokine that helps regulate the hematopoiesis of cells of the immune system is a colony-stimulating factor. The correct answer to the question is A. G-CSF (Granulocyte Colony-Stimulating Factor). G-CSF is one of the colony-stimulating factors, which are a group of glycoproteins that play a vital role in hematopoiesis. They function as autocrine or paracrine factors and are significant for their role in the proliferation and maturation of various blood cells, including those of the immune system. G-CSF specifically triggers the differentiation and proliferation of granulocytes from hematopoietic stem cells.

Other options mentioned (B. TNF-α, C. IFN-γ, D. IL-5) are different kinds of cytokines with varying roles in the immune response, but they are not the primary regulators of hematopoiesis. Interleukins, such as IL-5, do contribute to hematopoiesis by influencing the production of certain lymphocytes and other cells, but for the broad regulation of hematopoiesis of immune cells, G-CSF is the specific cytokine in this context.

Answer 2

The cytokine that regulates the hematopoiesis of cells of the immune system is the granulocyte colony-stimulating factor (G-CSF). It specifically promotes the proliferation and differentiation of granulocytes, a subset of white blood cells, thereby making it the correct option from the choices provided. A is the correct option.

Step-by-step explanation:

Cytokines are glycoproteins that serve as chemical messengers to regulate various processes in the body, including cell differentiation, proliferation, gene expression, and cell trafficking to effect immune responses. Among the cytokines, colony-stimulating factors (CSFs) and interleukins are particularly important in regulating hematopoiesis—the process where blood and immune cells are produced.

In the context of the student's question, the cytokine that helps regulate the hematopoiesis of cells of the immune system is a colony-stimulating factor.

Specifically, granulocyte colony-stimulating factor (G-CSF) is responsible for the proliferation and differentiation of granulocytes, which are types of white blood cells that play a crucial role in the immune response.