2.2k views
2 votes
What does the molecule B7 do? Where is it found? What does it bind to? What are it's other names?

1 Answer

5 votes

Final answer:

B7, also known as CD80 or CD86, is a costimulatory molecule on antigen-presenting cells that binds to CD28 on T cells to stimulate a proper immune response.

Step-by-step explanation:

The molecule referred to as B7 is actually a cluster of differentiation (CD) molecule found on antigen-presenting cells. It plays a critical role in the immune response by providing a costimulatory signal necessary for T cell activation and survival. B7 binds to CD28 on T cells, and this interaction is important for T cell proliferation and the production of interleukin-2. B7 has different isoforms, namely B7-1 (CD80) and B7-2 (CD86), and these molecules can be found on the surfaces of B cells, dendritic cells, and macrophages.

B7 is a vital part of the immune system and has also been referred to by other names such as CD80 and CD86 for its subtypes.B7, also known as CD80 or CD86, is a costimulatory molecule on antigen-presenting cells that binds to CD28 on T cells to stimulate a proper immune response.

User Tom West
by
8.4k points