Final answer:
The clamp should be placed on the west condenser when setting up for reflux with an RB flask, thermowell, and west condenser, to ensure stability and safety of the fragile component.
Step-by-step explanation:
When refluxing with an RB flask, thermowell, and west condenser, the clamp should be placed on the west condenser. This is because the condenser is the heaviest and most fragile component in this setup and needs to be securely fastened to prevent it from detaching and potentially causing breakage or injury. Also, clamping the condenser allows the RB flask to be freely moved or adjusted as needed without destabilizing the entire apparatus.
It is also essential to ensure that the clamp is not overtightened on the glassware as this can cause stress fractures. When assembling the reflux apparatus, the position of the clamp might depend on the specific setup, but generally, securing the condenser is the most common and safest practice.