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SIRT should have considerable influence over two major areas.

Those two areas are _____________ and _______________.

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Final answer:

SIRT should have considerable influence over aging and disease.

Step-by-step explanation:

The two major areas over which SIRT (sirtuins) should have considerable influence are aging and disease. Sirtuins are a group of proteins that play a crucial role in regulating cellular processes and metabolism. They have been linked to processes such as DNA repair, energy metabolism, and cellular survival, which are all key factors in aging and disease.

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