Final answer:
If end product E1 allosterically inhibits enzyme 1 and there is a buildup of E1 in the cell, it will decrease the production of substance E.
Step-by-step explanation:
In the given scenario, if end product E1 allosterically inhibits enzyme 1 and there is a buildup of E1 in the cell, it will decrease the production of substance E.
Allosteric inhibition occurs when the end product of a metabolic pathway binds to an enzyme and changes its shape, rendering it inactive. This is known as feedback inhibition. In this case, E1 binding to enzyme 1 inhibits its catalytic activity, thereby slowing down the entire pathway and reducing the production of substance E.
This regulatory mechanism ensures that the cell does not produce excessive amounts of substance E when it is not needed, preventing potential toxicity.