Final answer:
Yes, Jefferson's rationale in the Declaration of Independence was primarily influenced by John Locke, particularly his natural rights theory and the concept of social contract.
Step-by-step explanation:
The statement that Jefferson's rationale in the Declaration of Independence came primarily from the theories of John Locke is true. Thomas Jefferson was greatly influenced by Enlightenment thinkers, particularly John Locke.
Locke's philosophy included the concept of natural rights, including life, liberty, and property (which Jefferson adapted to "life, liberty, and the pursuit of happiness"), the idea of the social contract, and government's responsibility to protect these rights. If it fails to do so, according to Locke, citizens have the right to overthrow it.
These principles form the backbone of the Declaration of Independence, justifying the American colonies' separation from British rule.